Description
Tandospirone hydrochloride is a 5-HT1A receptor partial agonist (Ki = 27 nM) with selectivity over 5-HT2, 5-HT1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300 - 41000 nM). Tandospirone is inactive at 5-HT uptake sites, 5-HT1B, β-adrenergic, muscarinic and benzodiazepine receptors. Tandospirone is used in the treatment of anxiety and depression